All About Dim

3,3'-Diindolymethane (DIM) helps balance, normalise and improve estrogen metabolism in women and helps eliminate active estrogen from the male body by promoting its conversation into the “good” metabolites. 

Studies have shown that higher levels of testosterone and lower levels of estrogen have been linked to lean body mass, efficient fat-burning metabolising and reduction in abdominal fat. 

It has potent effects on estrogen metabolism and is able to keep the body relatively balanced (by preventing either drastic increases or decreases in estrogen). In small amounts, it can both inhibit the aromatase enzyme (and prevent conversion of testosterone into estrogen) and it can act on more potent forms of estrogen and convert them into less potent forms; this conversion reduces the overall effects of estrogen in the body.

DIM exerts numerous anti-carcinogenic (anti-cancer) effects in the body. It also simultaneously reduces the levels of harmful estrogen metabolites, which is beneficial because they are associated with an increased risk for obesity, breast cancer and uterine cancer. Additional problems associated with too many harmful oestrogen metabolites, include moodiness and breast pain in women and loss of sex drive in men; thus DIM can assist in reducing this adverse effects of unbalanced estrogen levels. 

Adding DIM into your supplement regime can assist you in hormone balance and hitting your health and fitness goals. Total Science Nutrition add's DIM to both our Rush Burn and Rush Pump to elevate hormone imbalance. 

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References: 

NYU Langone Medican Centre (http://www.med.nyu.edu/content?ChunkIID=104670)

Sanderson JT, Slobbe L, Lansbergen GW, Safe S, van den Berg M. 2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolylmethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells. Toxicol Sci . 2001;61:40–8.

WebMD (http://www.webmd.com/vitamins-supplements/ingredientmono-1049-diindolylmethane.aspx?activeingredientid=1049&activeingredientname=diindolylmethane)

Le HT, Schaldach CM, Firestone GL, Bjeldanes LF. Plant-derived 3,3'-diindolylmethane is a strong androgen antagonist in human prostate cancer cells. J Biol Chem . 2003;278:21136–45. Epub 2003 Mar 27.